A density-independent rigidity transition in biological tissues
نویسندگان
چکیده
منابع مشابه
A density-independent rigidity transition in biological tissues
Cell migration is important in many biological processes, including embryonic development, cancer metastasis, and wound healing. In these tissues, a cell’s motion is often strongly constrained by its neighbors, leading to glassy dynamics. While self-propelled particle models exhibit a density-driven glass transition, this does not explain liquid-to-solid transitions in confluent tissues, where ...
متن کاملA geometrically controlled rigidity transition in a model for confluent 3D tissues
The origin of rigidity in disordered materials is an outstanding open problem in statistical physics. Previously, a class of 2D cellular models has been shown to undergo a rigidity transition controlled by a mechanical parameter that specifies cell shapes. Here, we generalize this model to 3D and find a rigidity transition that is similarly controlled by the preferred surface area: the model is...
متن کاملBiological alterations in renal and hepatic tissues by a novel gold (III) anti-cancerous compound
Objective(s): Newer organo-metallic, specifically gold (III) complexes with multiple ligands are currently being formulated with primary focus of having increased anti-cancerous properties and decreased cytotoxicity. In this study, histological toxicity profile of a newly formulated anti-cancerous gold (III) compound [trans-(±)-1,2-(DACH)2Au]Cl3 Bis(trans-1,2-Diaminocyclohexane) was investigate...
متن کاملPhoton Diffusion in Biological Tissues
The use of laser-based optical techniques for medical imaging is an attractive alternative to other methods that utilize ionizing radiation. Beside being non-carcinogenic, it is non-invasive, the equipment is transportable, and the methodology can be used to examine properties of soft tissue. However, unlike x-ray photons, optical photons generated in the near-infrared suffer significant amount...
متن کاملCommentary: microparticles in biological tissues*
Depletion of skeletal muscle mass in animals bearing an experimental model of cachexia, the MAC16 adenocarcinoma, occurs by a reduction in protein synthesis accompanied by a large increase in protein degradation. Serum from mice bearing the MAC16 tumour produced an increased protein degradation in isolated gastrocnemius muscle, as measured by tyrosine release, with a maximal effect occurring wi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Physics
سال: 2015
ISSN: 1745-2473,1745-2481
DOI: 10.1038/nphys3471